DPP4 inhibitors to prevent aortic valve calcification

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Human aortic valve calcification.

To the Editor: Rajamannan et al1 addressed the problem of bone formation in calcified aortic valves, quoting the publication of actual bone formation by Mohler et al.2 Mohler et al had indicated that ossification in calcified aortic valves was relatively common, finding evidence of valve ossification in 36 of 323 patients. Of historical interest, I reported ossification in the left ventricular ...

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Citing this paper Please note that where the full-text provided on King's Research Portal is the Author Accepted Manuscript or Post-Print version this may differ from the final Published version. If citing, it is advised that you check and use the publisher's definitive version for pagination, volume/issue, and date of publication details. And where the final published version is provided on th...

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CONTEXT It is unclear whether cardiovascular disease is present in primary hyperparathyroidism (PHPT). OBJECTIVE Aortic valve structure and function were compared in PHPT patients and population-based controls. DESIGN This is a case-control study. SETTING The study was conducted in a university hospital metabolic bone disease unit. PARTICIPANTS We studied 51 patients with PHPT and 49 co...

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ژورنال

عنوان ژورنال: Nature Reviews Cardiology

سال: 2017

ISSN: 1759-5002,1759-5010

DOI: 10.1038/nrcardio.2017.28